Main Category: Prostate / Prostate Cancer
Also Included In: Urology / Nephrology
Article Date: 18 Jan 2012 - 14:00 PST
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A study by investigators at the Methodist Research Institute at Indiana University confirms that an all-natural, doctor-designed formula is effective in suppressing prostate cancer tumors. The study conducted on mice, used a human prostate cancer xenograft model.
Results from the live animal study were presented by lead researcher, Dr. Daniel Sliva at the 16th World Congress on Advances in Oncology in Rhodes, Greece and at the 14th International Symposium on Molecular Medicine.
The formula showed to be considerably effective in suppressing the proliferation and metastasis of human hormone refractory (androgen independent) prostate cancer cells. Furthermore, the formula was confirmed to be non-toxic and poses no risk of adverse effects.
Dr. Sliva, explains: "Dietary supplements are used as an alternative or adjuvant therapies. However, rigorous scientific verification of their biological activity in vitro and in vivo is necessary for the acceptance of dietary supplements in conventional cancer treatment and prevention."
The study is significant, as it is exceptionally hard to treat hormone refractory prostate cancer (androgen independent). Hormone refractory prostate cancer is the most aggressive, advanced form of the disease and usually leads to metastasis and progression of the cancer.
The ingredients of the formula, which contains botanical extracts, antioxidants, botanically enhanced medical mushrooms, and phytonutrients were chosen by the researchers based on scientific research showing their abilities to fight prostate abnormalities and provide extensive prostate support.
The researchers grafted human prostate cancer cells (tissues) onto mice using a xenograft model - where organs or tissue from an individual of one species is grafted or transplanted onto an organism of another species, genus, or family. The team found that oral administration of this natural formula produced a statistically significant suppression of tumor growth.
Study results also demonstrated that the formula worked to suppress several genes involved in cancer metastasis and proliferation. Two of the suppressed genes are associated to the metastatic potential. The genes can highlight the ability of this preparation to suppress the primary tumor growth as well as the metastatic process, a vital benefit in fighting this aggressive cancer.
Prior investigations studying this formula have been conducted at research laboratories at Columbia University, NY, NY, the Cancer Research Laboratory, Methodist Research Institute, and Indiana University health, Indianapolis, IN, using cell culture studies and gene expression analysis. These previous studies demonstrated considerable results in the formula's ability to suppress proliferation and prostate cancer growth.
The current study is a breakthrough in the investigation of this natural formula, as it used an xenograft model on mice to test for toxicity and demonstrated to inhibit tumor growth within a living mammal.
Dr. Sliva explained: "In summary, this dietary supplement is a natural compound for the possible therapy of human hormone refractory (independent) prostate cancer."
Current research on this formal continues to demonstrate positive results, and further investigations are to be conducted in the future.
Written By Grace Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
MLA
18 Jan. 2012.
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